Marc Bigaud Selected Research

NIBR-0213

1/2016	Pathophysiological Consequences of a Break in S1P1-Dependent Homeostasis of Vascular Permeability Revealed by S1P1 Competitive Antagonism.
9/2012	A potent and selective S1P(1) antagonist with efficacy in experimental autoimmune encephalomyelitis.

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Marc Bigaud Research Topics

Disease

4	Inflammation (Inflammations) 01/2020 - 01/2013
3	Multiple Sclerosis 01/2022 - 04/2011
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2022 - 09/2012
2	Lymphoma (Lymphomas) 12/2020 - 01/2020
2	Autoimmune Diseases (Autoimmune Disease) 12/2020 - 12/2019
2	Arthritis (Polyarthritis) 01/2020 - 01/2016
2	Necrosis 01/2016 - 03/2004
1	Retinal Degeneration 01/2022
1	Optic Neuritis (Retrobulbar Neuritis) 01/2022
1	Demyelinating Diseases (Demyelinating Disease) 01/2022
1	Neoplasms (Cancer) 01/2020
1	Idiopathic Thrombocytopenic Purpura (Thrombocytopenic Purpura, Autoimmune) 01/2020
1	Marginal Zone B-Cell Lymphoma (MALT Lymphoma) 01/2020
1	Sialadenitis 01/2019
1	Pathologic Processes 01/2019
1	Fibrosis (Cirrhosis) 01/2016
1	Edema (Dropsy) 01/2016
1	Hemorrhage 01/2016
1	Gliosis 05/2014
1	Atrophy 05/2014
1	Disease Progression 01/2014
1	Neointima 02/2004

Drug/Important Bio-Agent (IBA)

3	Peptide Hydrolases (Proteases)FDA Link 01/2020 - 12/2019
2	Sphingosine-1-Phosphate ReceptorsIBA 01/2022 - 04/2011
2	Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 ProteinIBA 12/2020 - 04/2015
2	AutoantibodiesIBA 01/2020 - 01/2019
2	NIBR-0213IBA 01/2016 - 09/2012
2	Pharmaceutical PreparationsIBA 05/2014 - 01/2014
2	Fingolimod Hydrochloride (FTY720)FDA Link 09/2012 - 04/2011
1	RNA (Ribonucleic Acid)IBA 01/2022
1	Retinaldehyde (Retinal)IBA 01/2022
1	siponimodIBA 01/2022
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2020
1	Immunoglobulin E (IgE)IBA 01/2020
1	Inosine Triphosphate (ITP)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	CytokinesIBA 01/2020
1	Therapeutic UsesIBA 01/2019
1	Biomarkers (Surrogate Marker)IBA 01/2014
1	sphingosine 1-phosphate lyase (aldolase)IBA 01/2013
1	SphingolipidsIBA 01/2013
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 04/2011
1	DiureticsIBA 03/2004
1	Vasoconstrictor AgentsIBA 02/2004

Therapy/Procedure

1	Oral Administration 04/2011